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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FGFR3
All Species:
28.48
Human Site:
S445
Identified Species:
56.97
UniProt:
P22607
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22607
NP_000133.1
806
87710
S445
V
R
I
A
R
L
S
S
G
E
G
P
T
L
A
Chimpanzee
Pan troglodytes
XP_521622
819
91776
T452
I
T
T
R
L
S
S
T
A
D
T
P
M
L
A
Rhesus Macaque
Macaca mulatta
XP_001101108
806
87642
S445
V
R
I
A
R
L
S
S
G
E
G
P
T
L
A
Dog
Lupus familis
XP_545926
833
90729
S472
V
R
I
A
R
L
S
S
G
E
G
P
A
L
A
Cat
Felis silvestris
Mouse
Mus musculus
Q61851
801
87739
S439
V
R
I
A
R
L
S
S
G
E
G
P
V
L
A
Rat
Rattus norvegicus
Q04589
822
91806
S451
V
R
P
S
R
L
S
S
S
G
T
P
M
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P18460
806
89712
S439
V
R
I
T
R
L
S
S
S
D
G
P
M
L
A
Frog
Xenopus laevis
O42127
802
89497
S435
V
R
I
T
H
L
S
S
S
D
G
T
M
L
A
Zebra Danio
Brachydanio rerio
Q9I8X3
800
89698
S433
V
R
I
A
R
L
S
S
S
D
G
P
M
L
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q07407
729
82568
F403
A
P
F
N
E
Y
E
F
P
L
D
S
N
W
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10656
1040
118938
K613
E
A
A
R
K
Q
R
K
R
M
N
S
E
N
T
Sea Urchin
Strong. purpuratus
Q26614
972
110463
N612
A
P
L
F
G
G
R
N
R
L
T
S
S
L
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.2
99.1
89.3
N.A.
92.4
62.9
N.A.
N.A.
80.1
70.5
73.8
N.A.
37.5
N.A.
31.3
35.4
Protein Similarity:
100
77.5
99.2
91.9
N.A.
94.7
76.2
N.A.
N.A.
87.5
79.4
82.3
N.A.
54
N.A.
46.6
50
P-Site Identity:
100
26.6
100
93.3
N.A.
93.3
60
N.A.
N.A.
73.3
60
73.3
N.A.
0
N.A.
0
6.6
P-Site Similarity:
100
46.6
100
93.3
N.A.
93.3
66.6
N.A.
N.A.
80
66.6
80
N.A.
0
N.A.
6.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
9
9
42
0
0
0
0
9
0
0
0
9
0
67
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
34
9
0
0
0
0
% D
% Glu:
9
0
0
0
9
0
9
0
0
34
0
0
9
0
9
% E
% Phe:
0
0
9
9
0
0
0
9
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
9
9
0
0
34
9
59
0
0
0
0
% G
% His:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
0
59
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
9
0
0
9
0
0
0
0
0
0
0
% K
% Leu:
0
0
9
0
9
67
0
0
0
17
0
0
0
84
0
% L
% Met:
0
0
0
0
0
0
0
0
0
9
0
0
42
0
0
% M
% Asn:
0
0
0
9
0
0
0
9
0
0
9
0
9
9
0
% N
% Pro:
0
17
9
0
0
0
0
0
9
0
0
67
0
0
9
% P
% Gln:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
67
0
17
59
0
17
0
17
0
0
0
0
0
0
% R
% Ser:
0
0
0
9
0
9
75
67
34
0
0
25
9
0
0
% S
% Thr:
0
9
9
17
0
0
0
9
0
0
25
9
17
0
17
% T
% Val:
67
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% W
% Tyr:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _